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Interventional Cardiovascular Associates, P.A.
20 Prospect Avenue
Suite 503
Hackensack, NJ 07601
Tel: 201.996.1444

Physicians

Joseph G. Wiedermann, M.D., F.A.C.C. Clinical Trials and Publications

Research Experience

  1. SPIRIT III Clinical Trial: A Clinical Evaluation of the XIENCE Everolimus Eluting Coronary Stent System in the Treatment of Subjects with de novo Native Coronary Artery Lesions Ongoing trial: Dr. Wiedermann co-investigator at Hackensack University Medical center site.
  2. FUTURE IV Clinical Trial: A Clinical Evaluation of the CHAMPION Everolimus Eluting Stent System in the Treatment of Patients with de novo Native Coronary Artery Lesions Ongoing trial: Dr. Wiedermann co-investigator at Hackensack University Medical center site.
  3. TAXUS IV Clinical Trial: A polymer-based paclitaxel-eluting stent in patients with coronary artery disease. Completed trial: Dr. Wiedermann co-investigator at Hackensack University Medical center site.
  4. Biliary Stenting in Saphenous Vein Grafts: Assessment of Acute Success, Procedural Complications, and Clinical Restenosis Benefit as Compared to Historical Balloon Angioplasty Therapy. Completed trial: Dr. Wiedermann principal investigator at Hackensack University Medical center site.
  5. Coronary Angioplasty and Rotoblator Atherectomy Trial (CARAT) Multi-center trial: Dr. Wiedermann co-investigator at Hackensack University Medical center site.
  6. Phase I Investigation of Intracoronary Irradiation For The Prevention of Restenosis Post-Angioplasty in Humans. Completed trial: Dr. Wiedermann co-investigator at Hackensack University Medical center site.
  7. Trial of the Schneider Wallstent for Diffusely Diseased Saphenous Vein Grafts: Comparison to Outcomes With Balloon Angioplasty. Completed trial: Dr. Wiedermann principal investigator at Hackensack University Medical center site.
  8. Trial of the Bard XT Stent for focal CAD; comparison with first generation stent designs. Completed trial: Dr. Wiedermann co-investigator at Hackensack University Medical center site.
  9. Prospective Single-Center Study of Transplant Coronary Artery Disease Assessed by Intravascular Ultrasound With Angiographic Correlation. Initial results presented at the November 1994 AHA Meetings. Ongoing investigational protocol; Columbia University.
  10. Investigation of the Effect of Intracoronary Irradiation on Coronary Vasomotion and Coronary Structural Morphology in a Porcine Model. Initial results presented at the November 1992 AHA Meetings.Subsequent publication: American Journal of Physiology 1994;267(36): H125-H132.
  11. Intracoronary Irradiation and its Effects on Restenosis in a Porcine Balloon Overdilatation Model. Initial results presented at the November 1993 and 1994 AHA Meetings.First paper: Journal of the American College of Cardiology 1994;23:1491-8. Second paper: Journal of the American College of Cardiology 1995;25:1451-6.
  12. Intravascular Ultrasound Imaging of Angiographically Normal Coronary Arteries in Patients with Chest Pain Syndromes: A Morphological and Dynamic Investigation During Rest and Exercise, Before and After Intravenous Propranolol, with a Two Year Prospective Study of Clinical Course. Initial results presented at the November 1993 and 1994 AHA meetings; JACC 1995;25:1310-7.
  13. Intravascular Ultrasound Imaging of Extracranial Carotid Artery Disease: Comparison to Conventional Non-Invasive Sonography with Particular Emphasis on Carotid Territory Inadequately Imaged by Conventional Techniques. Initial results presented at the November 1993 AHA Meetings.

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Publications

TAXUS IV Investigators. A polymer-based paclitaxel-eluting stent in patients with coronary artery disease. N Engl J Med 2004;350:221-231.

Roger H. Coletti, Bruce J. Haik, Joseph G. Wiedermann. Use of the Intra-aortic Balloon Pump as an Aortic Cross-clamp to Maximize Effectiveness of CPR in Humans. Journal of the American College of Cardiology 1996: March Supple; Abstract #1280.

Leslie Miller, Jon Kobashigawa, Paul Hauptman, Hannah Valantine, Hector Ventura, Jacqueline O'Donnell, Alan Yeung, Joseph Wiedermann, Terry Greenwalt, for the Sandoz/CVIS Investigators. Definition of Critical Cyclosporine Level for Preventing Rejection in Heart Transplant Patients. Journal of Heart-Lung Transplantation 1996: March Suppl.; Abst.

Roger H. Coletti, Bruce J. Haik, Joseph G. Wiedermann. Marked Reduction in Slow-Reflow After Rotational Atherectomy Through the Use of a Novel Flushing Solution. Journal of Invasive Cardiology 1996; 8 (1):32.

Weinberger J, Amols H, Ennis R, Schwartz A, Wiedermann J, Marboe C. Intracoronary irradiation: dose response for the prevention of restenosis in swine. Int J Radiat Oncol Biol Phys. 1996;36:767-775.

Miller L, Kobashigawa J, Valantine H, Ventura H, Hauptman P, O'Donnell J, Wiedermann J, Yeung A. The Impact of Cyclosporine Dose and Level on the Development and Progression of Allograft Coronary Disease. The Journal of Heart and Lung Transplantation. 1995; 14 (6, Pt. 2): S227-232.

Wiedermann JG, Marboe C, Amols H, Schwartz A, Weinberger J. Intracoronary Irradiation Markedly Reduces Restenosis after Balloon Angioplasty in a Porcine Model. Journal of the American College of Cardiology 1994;23:1491-8.

Wiedermann JG, Leavy JA, Amols H, Schwartz A, Homma S, Marboe C, Weinberger J. Effects of High Dose Intracoronary Irradiation on Vasomotor Function and Smooth Muscle Histopathology. American Journal of Physiology 1994;267(36): H125-H132.

Wiedermann JG, Schwartz A, Apfelbaum M. Anatomic and Physiologic Heterogeneity in Syndrome X Patients: An Intravascular Ultrasound Study. Journal of the American College of Cardiology 1995;25:1310-7.

Wiedermann JG, Marboe C, Amols H, Schwartz A, Weinberger J. Intracoronary Irradiation Markedly Reduces Restenosis after Balloon Angioplasty in a Porcine Model: Six Month Follow-Up. Journalof the American College of Cardiology 1995;25:1451-6.

Wiedermann JG, Marboe C, Amols H, Schwartz A, Weinberger J. Intracoronary Irradiation: Minimal Effective Dose for Prevention of Restenosis in Swine. Journal of the American College of Cardiology (manuscript in press).

Wiedermann JG, Marboe C, Amols H, Schwartz A, Weinberger J. Intracoronary Irradiation Fails to Reduce Neointimal Proliferation After Oversized Stenting in a Porcine Model. Circulation 1995;92 (8); I-146: 0690.

Wiedermann JG, Wasserman HS, Weinberger J, Schwartz A, Apfelbaum M. Severe Intimal Thickening by Intracoronary Ultrasound Predicts Early Death in Cardiac Transplant Recipients. Circulation 1994;90:I-93.

Wiedermann JG, Drusin R, Levin H, Schwartz A, Apfelbaum M. Unexplained Heart Failure in Cardiac Transplant Recipients: Intracoronary Ultrasound Identifies Two Distinct Subgroups. Journal of the American College of Cardiology, February 1995; Abstract #784-6: 334A.

Wiedermann JG, Wasserman HS, Weinberger J, Schwartz A, Apfelbaum M. Coronary Vasomotion in Syndrome X Patients: An Intravascular Ultrasound Study of Exercise Response and Propranolol Effect. Circulation 1994;90:I-58.

Wiedermann JG, Marboe C, Amols H, Schwartz A, Weinberger J. Intracoronary Irradiation: Minimal Effective Dose for Prevention of Restenosis in Swine. Circulation 1994;90:I-59.

Wiedermann JG, Marboe C, Amols H, Schwartz A, Weinberger J. Intracoronary Irradiation Markedly Reduces Restenosis after Balloon Angioplasty in a Porcine Model: Six Month Follow-Up. Circulation 1994;90:I-652.

Wiedermann J, Wasserman HS, Weinberger J, Schwartz A, Homma S, Apfelbaum M. Anatomic and Physiologic Heterogeneity in Syndrome X Patients: An Intravascular Ultrasound Study. Circulation 1993; 88: I-549.

Wiedermann J, Marboe C, Amols H, Schwartz A, Weinberger J. Intracoronary Irradiation Markedly Reduces Restenosis after Balloon Angioplasty in a Porcine Model. Circulation 1993; 88: I-655.

Wiedermann J,Mohr JP, Homma S, Schwartz A, Apfelbaum M. Transvenous Carotid Ultrasound Imaging: A Novel Approach to Visualization of the Extracranial Carotid Artery. Circulation 1993; 88: I-658.

Wiedermann J, Leavy J, Amols H, Homma S, Di Tullio M, Sherman D, Apfelbaum M, Schwartz A, Weinberger J. Intracoronary Irradiation Acutely Impairs Endothelial and Smooth Muscle Function as Assessed by Intravascular Ultrasound. Circulation 1992;86: I-188.

Mathan V I, Wiedermann J, et. al. Geographical Differences in Digoxin Inactivation, a Metabolic Activity of the Human Anaerobic Gut Flora. Gut :1989 July ;30(7), 971-77.

Symposia

Second Annual Symposium on Cardiac Allograft Vasculopathy. St. Louis, MO. Featured Speaker. Topic: Can Measurement of Intimal Thickening by ICUS Predict Clinical Outcome in Cardiac Transplant Patients? 5/95

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